NESA Biology Causes of Infectious Disease

15 sample questions with marking guides and sample answers · Avg. score: 68.5%

Q2
2025
SCSA
1 mark
Q2
1 mark

Malaria can be spread when a mosquito carrying the parasite bites a non-infected person. This is an example of

A

transmission by direct contact.

B

vector transmission.

C

infection by droplets.

D

airborne transmission.

Reveal Answer
A

transmission by direct contact.

Direct contact transmission requires physical contact between an infected person and a susceptible person, not an intermediate organism like a mosquito.

B

vector transmission.

Correct Answer

Vector transmission occurs when a living organism, such as a mosquito or tick, carries and transmits an infectious pathogen to another living organism.

C

infection by droplets.

Droplet transmission occurs when respiratory droplets from coughing or sneezing carry pathogens directly to a susceptible person, which does not involve a mosquito.

D

airborne transmission.

Airborne transmission involves pathogens traveling through the air over time and distance, rather than being delivered by a biting insect.

Q12
2024
NESA
1 mark
Q12
1 mark

Robert Koch produced a set of criteria to establish whether a particular organism is the cause of a disease in an animal. The criteria are listed below but not in the correct order.

  1. The microorganism must cause disease when introduced to a healthy experimental animal.
  2. The microorganism must be extracted and isolated from the diseased animal and subsequently grown in culture.
  3. The microorganism must be extracted from the diseased experimental animal and demonstrated to be the same microorganism that was isolated from the first diseased animal.
  4. The microorganism must be found in the diseased animal, and not found in healthy animals.

Which of the following correctly shows the order of steps required to determine the cause of a particular disease in an animal?

A

2, 3, 1, 4

B

2, 4, 1, 3

C

4, 2, 1, 3

D

4, 3, 2, 1

Reveal Answer
A

2, 3, 1, 4

This order incorrectly starts with isolating the microorganism before first establishing its presence in diseased animals and absence in healthy ones.

B

2, 4, 1, 3

This sequence is incorrect because it suggests isolating the microorganism before confirming it is exclusively found in diseased animals.

C

4, 2, 1, 3

Correct Answer

This correctly follows Koch's postulates: first identify the pathogen in diseased animals (4), isolate and culture it (2), infect a healthy animal to cause disease (1), and finally reisolate it to confirm identity (3).

D

4, 3, 2, 1

This order is incorrect because it places the re-isolation of the microorganism from the experimental animal before actually infecting the healthy experimental animal.

Q1
2023
SCSA
1 mark
Q1
1 mark

Phytophthora is a pathogen that infects

A

Australian native plants only.

B

Australian native animals only.

C

a broad range of plants.

D

a broad range of animals.

Reveal Answer
A

Australian native plants only.

While Phytophthora is a major threat to many Australian native plants, it is not restricted to them and infects plants worldwide.

B

Australian native animals only.

Phytophthora is a plant pathogen (a type of water mold) and does not infect animals.

C

a broad range of plants.

Correct Answer

Phytophthora is a genus of destructive water molds that are known to infect a wide variety of plant species globally, causing diseases like root rot and potato blight.

D

a broad range of animals.

Phytophthora specifically targets and infects plants, not animals.

Q5
2024
SCSA
1 mark
Q5
1 mark

Most pathogens can evolve rapidly because they have

A

complex life cycles.

B

simple life cycles.

C

long generation times.

D

short generation times.

Reveal Answer
A

complex life cycles.

While some pathogens have complex life cycles, this complexity does not inherently cause rapid evolution and can sometimes slow down the reproductive rate.

B

simple life cycles.

Although many pathogens have simple life cycles, simplicity alone does not drive rapid evolution; the speed of reproduction is the critical factor.

C

long generation times.

Long generation times would actually slow down evolution, as it takes more time for new mutations to arise and be passed on to subsequent generations.

D

short generation times.

Correct Answer

Short generation times allow pathogens to reproduce very quickly, providing more opportunities for mutations to occur and be selected for, which drives rapid evolution.

Q34
2025
SCSA
20 marks
Q34c

The major groups of organisms that cause infectious disease are bacteria, fungi, protists and viruses. Two new chemical treatments have been developed for treating some infectious diseases. Treatment A acts by destroying chitin molecules. Treatment B acts by destroying cellulose molecules.

Q34a
4 marks

Identify two errors in the following statement about crown gall disease and, in each case, justify your answer.

Crown gall is a viral, waterborne disease of plants.

Reveal Answer

Error 1: stating that crown gall is a viral disease -- crown gall is caused by a bacterium.

Error 2: stating that crown gall is a waterborne disease -- crown gall is a soilborne disease and is transmitted through contaminated soil or equipment.

Marking Criteria
DescriptorMarks

Identifies the first error as stating crown gall is a viral disease

1

Justifies this by stating crown gall is caused by a bacterium

1

Identifies the second error as stating crown gall is a waterborne disease

1

Justifies this by stating crown gall is a soilborne disease or is transmitted through contaminated soil or equipment

1
Q34b
4 marks

Describe how the crown gall pathogen causes disease.

Reveal Answer

The pathogen DNA is inserted into the host genome, and this inserted DNA contains hormone genes. These genes cause rapid cell division, which disrupt the transport of water and nutrients. The galls divert energy from normal growth in the host, hence plant growth slows.

Marking Criteria
DescriptorMarks

1 mark for each correct point (any 4 of):
Describes that pathogen DNA/plasmid is inserted into the host genome; States that the inserted DNA/plasmid contains hormone genes;
Explains that these genes cause excessive/rapid cell division or galls in the host;
States that this disrupts the transport of water/nutrients;
Explains that galls divert energy from normal growth in the host;
Concludes that plant growth slows, the plant wilts, productivity is reduced, plants are less able to tolerate stressful conditions, or plants die/are unhealthy

4
Q34c (i)
1 mark

State one pathogen group that might be harmed by Treatment A.

Reveal Answer

Fungi.

Marking Criteria
DescriptorMarks

Identifies fungi

1
Q34c (ii)
2 marks

Outline how Treatment A might harm the pathogen group stated in part (c)(i).

Reveal Answer

Chitin is present in fungal cell walls, so the treatment will destroy the cell walls.

Marking Criteria
DescriptorMarks

States that chitin is present in fungal cell walls

1

Explains that the treatment will destroy the cell walls, cause cells to rupture, or kill the cells

1
Q34c (iii)
3 marks

Evaluate whether Treatment A might be an effective treatment for Phytophthora dieback in plants.

Reveal Answer

It would be ineffective because the Phytophthora pathogen is a protist and it does not have chitin in its cell wall.

Marking Criteria
DescriptorMarks

Clearly states that the treatment is ineffective

1

Identifies that the Phytophthora pathogen is a protist

1

Explains that it does not have chitin in its cell wall

1
Q34c (iv)
3 marks

Evaluate whether Treatment B might be an effective treatment for Phytophthora dieback in plants.

Reveal Answer

It would be ineffective because both the Phytophthora pathogen and the plant host have cellulose in their cell walls. The treatment would therefore harm or kill the host plant as well.

Marking Criteria
DescriptorMarks

Clearly states that the treatment is ineffective

1

Identifies that both the Phytophthora pathogen and the plant host have cellulose in their cell walls

1

Explains that the treatment would therefore harm or kill the host plant as well

1
Q34d
3 marks

Health departments across Australia recommend that owners of rainwater tanks install mesh netting on all inlets and outlets of the tank.

Explain how mesh netting installed on tank inlets and outlets can assist in controlling the spread of Ross River fever.

Reveal Answer

Ross River fever is transmitted by mosquitoes, and mosquitoes can breed in tanks. The mesh stops the mosquitoes from entering the tank and disrupts the life cycle of the mosquito.

Marking Criteria
DescriptorMarks

States that Ross River fever is transmitted by mosquitoes

1

Identifies that mosquitoes can breed in tanks

1

Explains that mesh/netting stops mosquitoes entering the tank or disrupts the life cycle of the mosquito/pathogen

1
Q26
2024
NESA
4 marks
Q26
4 marks

Describe a plant disease and its effect on agricultural production.

Reveal Answer

Stone fruit scab

This is a fungal disease that affects stone fruit such as plums, peaches and nectarines. It starts as small dark spots on the fruit which later become scabby and may cause the fruit to crack, shrivel and fall off the plant.

It causes downgrading of fruit quality and decreased fruit yield, leading to economic losses.

Marking Criteria
DescriptorMarks

Describes a named plant disease and its effects on agriculture

4

Outlines a plant disease and its effect on agriculture

3

Demonstrates some understanding of a plant disease or its effects on agriculture

2

Provides some relevant information

1

None of the above

0
Q15
2020
SCSA
1 mark
Q15
1 mark

The amphibian chytrid pathogen causes disease in frogs by invading the

A

lungs and reducing the ability of the frog to breathe.

B

mouth and reducing the ability of the frog to breathe.

C

kidneys and reducing the ability of the frog to exchange water and gases.

D

skin and reducing the ability of the frog to exchange water and gases.

Reveal Answer
A

lungs and reducing the ability of the frog to breathe.

The chytrid fungus does not primarily invade the lungs; it specifically targets keratinized tissues on the outside of the body.

B

mouth and reducing the ability of the frog to breathe.

While the fungus can infect the keratinized mouthparts of tadpoles, the primary cause of fatal disease in adult frogs is not the invasion of the mouth.

C

kidneys and reducing the ability of the frog to exchange water and gases.

The pathogen does not invade internal organs like the kidneys; it is an external infection that affects the epidermis.

D

skin and reducing the ability of the frog to exchange water and gases.

Correct Answer

The amphibian chytrid fungus (Batrachochytrium dendrobatidis) infects the keratinized skin of frogs. Because amphibians rely heavily on their skin for respiration and osmoregulation, this infection disrupts their ability to exchange water and gases, ultimately leading to death.

Q2
2020
SCSA
1 mark
Q2
1 mark

A virus consists of a

A

protein coat and a nucleic acid.

B

protein coat and ribosomes.

C

cell wall and a nucleic acid.

D

cell wall and ribosomes.

Reveal Answer
A

protein coat and a nucleic acid.

Correct Answer

This is correct because the basic structure of a virus is a genome (nucleic acid, either DNA or RNA) enclosed in a protective protein coat known as a capsid.

B

protein coat and ribosomes.

This is incorrect because viruses lack ribosomes and other cellular machinery, requiring them to hijack a host cell to synthesize proteins.

C

cell wall and a nucleic acid.

This is incorrect because viruses are acellular and do not have cell walls, which are structures typically found in bacteria, plants, and fungi.

D

cell wall and ribosomes.

This is incorrect because viruses lack both cell walls and ribosomes, as they are not true cells and rely entirely on host organisms for reproduction.

Q8
2020
SCSA
1 mark
Q8
1 mark

Crown gall in plants is caused by

A

a DNA virus.

B

an RNA virus.

C

Agrobacterium.

D

Phytophthora.

Reveal Answer
A

a DNA virus.

Crown gall is a bacterial disease, not a viral infection caused by a DNA virus.

B

an RNA virus.

Crown gall is caused by a bacterium, not an RNA virus.

C

Agrobacterium.

Correct Answer

Crown gall disease is caused by the soil bacterium Agrobacterium tumefaciens, which transfers a piece of its tumor-inducing (Ti) plasmid DNA into the plant's genome.

D

Phytophthora.

Phytophthora is a genus of plant-damaging oomycetes (water molds) responsible for diseases like potato late blight, not crown gall.

Q9
2023
SCSA
1 mark
Q9
1 mark

The pathogen that causes malaria

A

is transmitted by Aedes mosquitoes.

B

typically kills both the human and mosquito hosts.

C

infects the salivary glands of humans.

D

multiplies in human liver and red blood cells.

Reveal Answer
A

is transmitted by Aedes mosquitoes.

Malaria is transmitted by Anopheles mosquitoes, not Aedes mosquitoes, which are known for transmitting diseases like dengue and Zika.

B

typically kills both the human and mosquito hosts.

While malaria can be fatal to humans, it does not typically kill the mosquito host, as the Plasmodium parasite relies on the mosquito to complete its life cycle and spread.

C

infects the salivary glands of humans.

The malaria pathogen infects the salivary glands of the mosquito, not the human. In humans, the infection targets the liver and blood.

D

multiplies in human liver and red blood cells.

Correct Answer

After entering the human bloodstream, Plasmodium parasites travel to the liver to multiply, and subsequently infect and multiply within red blood cells.

Q20
2022
VCAA
1 mark
Q20
1 mark

During their lifetime, plants are exposed to both pathogenic and beneficial microorganisms. Some plants provide shelter within their bodies for beneficial microorganisms. These beneficial microorganisms help plants that have not been genetically modified to resist pathogenic microorganisms.

The beneficial microorganisms may be providing protection by

A

synthesising toxins that kill pathogenic microorganisms.

B

providing a permeable physical barrier to pathogenic microorganisms.

C

stimulating the production of antibodies against pathogenic microorganisms.

D

mobilising the cells of the third line of defence against pathogenic microorganisms.

Reveal Answer
A

synthesising toxins that kill pathogenic microorganisms.

Correct Answer

Beneficial microorganisms can produce antimicrobial compounds or toxins that directly inhibit or kill pathogenic microorganisms, thereby protecting the plant.

B

providing a permeable physical barrier to pathogenic microorganisms.

A permeable barrier would allow substances, including pathogens, to pass through, which would not provide effective physical protection.

C

stimulating the production of antibodies against pathogenic microorganisms.

Plants do not possess an adaptive immune system and therefore cannot produce antibodies.

D

mobilising the cells of the third line of defence against pathogenic microorganisms.

The third line of defence refers to the adaptive immune system (involving B and T cells), which is present in vertebrates but absent in plants.

Q3
2022
SCSA
1 mark
Q3
1 mark

Tuberculosis is

A

a viral disease of the nervous system.

B

a fungal disease of the lungs.

C

transmitted by a vector.

D

transmitted by airborne particles.

Reveal Answer
A

a viral disease of the nervous system.

Tuberculosis is caused by a bacterium (Mycobacterium tuberculosis), not a virus, and it primarily affects the lungs rather than the nervous system.

B

a fungal disease of the lungs.

While tuberculosis does primarily affect the lungs, it is a bacterial infection, not a fungal disease.

C

transmitted by a vector.

Tuberculosis is not transmitted by a vector (such as a mosquito or tick); it is spread directly from person to person.

D

transmitted by airborne particles.

Correct Answer

Tuberculosis is an infectious bacterial disease that is spread from person to person through airborne particles when an infected person coughs or sneezes.

Q11
2023
SCSA
1 mark
Q11
1 mark

In crown gall disease, the galls are made up of

A

bacterial cells.

B

fungal cells.

C

protist cells.

D

host cells.

Reveal Answer
A

bacterial cells.

While crown gall disease is caused by bacteria (Agrobacterium tumefaciens), the galls themselves are not made of bacterial cells, but rather the plant's own cells.

B

fungal cells.

Crown gall disease is a bacterial infection, not a fungal one, and the resulting galls are composed of plant tissue.

C

protist cells.

The disease is caused by a bacterium, not a protist, and the galls consist of the host plant's cells.

D

host cells.

Correct Answer

The galls are tumors formed by the uncontrolled division of the plant's own cells (host cells) after their DNA is altered by the infecting bacteria.

Q17
2020
SCSA
1 mark
Q17
1 mark

Climate change is affecting the distribution of Ross River virus through its effects on activity and reproduction in the

A

viral pathogen.

B

bacterial pathogen.

C

human host.

D

mosquito vector.

Reveal Answer
A

viral pathogen.

While temperature can influence viral replication rates within the host, climate change primarily alters the disease's distribution by impacting the vector's life cycle and habitat, rather than the virus itself.

B

bacterial pathogen.

Ross River virus is a viral pathogen, not a bacterial one, making this option factually incorrect.

C

human host.

Although human behavior may shift with climate, the primary driver of the virus's changing geographic distribution is the environmental impact on its mosquito vector, not human reproduction or activity.

D

mosquito vector.

Correct Answer

Ross River virus is transmitted by mosquitoes. Climatic factors like temperature and rainfall directly dictate the breeding, survival, and geographic range of these mosquito vectors.

Q11
2025
SCSA
1 mark
Q11
1 mark

Viruses are surrounded by a protein coat. The viral protein is translated by

A

host ribosomes.

B

viral ribosomes.

C

host DNA.

D

viral DNA or RNA.

Reveal Answer
A

host ribosomes.

Correct Answer

Viruses lack their own cellular machinery, so they must hijack the host cell's ribosomes to translate viral mRNA into viral proteins.

B

viral ribosomes.

Viruses are acellular and do not contain their own ribosomes or other organelles required for protein synthesis.

C

host DNA.

DNA stores genetic information and is transcribed into RNA, but it is not the machinery that performs the translation of proteins.

D

viral DNA or RNA.

While viral DNA or RNA provides the genetic blueprint for the viral proteins, the actual translation process is carried out by ribosomes, not the nucleic acids themselves.

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